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Case Study A 19-year-old African-American female, hereinafter referred to equally “AP”, presents to her primary tending physician with fatigue duty, fever, and conservative upper quadrant (RUQ) abdominal pain for 3 days. AP has a epochal medical history of sickle cell anaemia (SCA).
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A 20-year-old africa- america woman visits her physical complaining of episodes of extreme pain and discomfort in her legs and lower back.
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It is recessive and joined to the ten chromosome.
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The most acute symptoms of the disease occur during geological period of exacerbation known as crises.
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Sickle cadre anemia is letter a genetic disease with severe symptoms, including pain and anemia.
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Essay on sickle cell anemia
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Anaemia is an abnormalcy in the consistency of a person.
At any time, the patient with reap hook cell disease bum be faced with a myriad of potentially life-threatening and unpredictable complications.
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She has been experiencing these recurrent episodes, accompanied by distant fatigue, since she was a child.
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What are the risks of sickle cell anemia?
Sickle cell disease, or sickle cell anemia, can increase risk of complications including: stroke, pulmonary hypertension, organ damage, blindness, vascular damage, gallstones, etc. For the purposes of this case study, AP will need to be monitored specifically for pulmonary, vascular, and neurological complications.
What is the history of sickle cell anemia?
There is history of sibling death at 5 years of age due to fever and jaundice. The hemogram showed anemia with leukocytosis. Red cell morphology (Figure 1) revealed severe anisopoikilocytosis with macrocytes, microcytic hypochromic red cells, target cells, many boat cells, sickled RBCs, polychromatic cells and occasional nucleated RBCs.
What are the different types of sickle cell disease?
Sickle cell disease is an umbrella term for individuals who express an abnormal gene that causes the body to make hemoglobin (Hb) S. The different types of SCD are Hb SβO thalassemia, Hb Sβ+ thalassemia, HbSC, HbSD, HbSE, and HbSS (NHLBI, n.d.). AP has HbSS which is the most common and most severe form of SCD.
How is DNA analysis used to diagnose sickle cell anemia?
To confirm the diagnosis, DNA analysis can be utilized. This exam is used to detect alterations and mutations in the genes producing hemoglobin components. DNA analysis reveals one copy or two copies of the hemoglobin S gene, or copies of different hemoglobin variants.
Last Update: Oct 2021
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On physical exam, she appears unhealthy and has A hematocrit.
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